GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs9473555 | 1 | rs12202075 | chr6:49427655 | CENPQ | chr6:49431096-49460820:+ | -0.25 | -4.33 | 3.64E-5 | Folate pathway vitamin levels |
| THYM | cis | rs9473555 | 1 | rs12202075 | chr6:49427655 | MUT | chr6:49398994-49431031:- | 0.28 | 4.21 | 5.84E-5 | Folate pathway vitamin levels |
| THYM | cis | rs1577917 | 1 | rs12203493 | chr6:86758642 | SNHG5 | chr6:86386726-86388451:- | -0.59 | -7.17 | 1.63E-10 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs12203924 | chr6:86776412 | SNHG5 | chr6:86386726-86388451:- | -0.59 | -7.17 | 1.63E-10 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs12204015 | chr6:86598334 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -7.62 | 1.9E-11 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs12204365 | chr6:86700532 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.89 | 5.95E-10 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs12205336 | chr6:86722367 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.96 | 4.28E-10 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs12205548 | chr6:86759770 | SNHG5 | chr6:86386726-86388451:- | -0.62 | -7.46 | 4.09E-11 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs12207305 | chr6:86723502 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.89 | 5.95E-10 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs12207610 | chr6:86688016 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.89 | 5.95E-10 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs12208493 | chr6:86662267 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.96 | 4.28E-10 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs12209127 | chr6:86724427 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.96 | 4.28E-10 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs12212733 | chr6:86726013 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.89 | 5.95E-10 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs12213149 | chr6:86668644 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.96 | 4.28E-10 | Response to antipsychotic treatment |
| THYM | cis | rs1577917 | 1 | rs12213740 | chr6:86656733 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.89 | 5.95E-10 | Response to antipsychotic treatment |